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Calreticulin 抗体 (C-Term)

This 兔多克隆 antibody specifically detects Calreticulin in WB 和 IHC. It exhibits reactivity toward 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, 马, 斑马鱼, Saccharomyces cerevisiae 和山羊.It has been mentioned in 1 publication

CALR antibody - C-terminal region (ARP30114_P050) Catalog Number: ARP30114_P050 Formalin Fixed Paraffin Embedded Tissue: Human Bronchial Epithelial Tissue Observed Staining: Cytoplasm and membrane of bronchial epithelial tissue Primary Antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0. (Calreticulin 抗体 (C-Term))

IHC

2 images

(1 reference)

产品编号 ABIN2779285

发货至: 中国

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Quick Overview for Calreticulin 抗体 (C-Term) (ABIN2779285)

抗原

See all Calreticulin (CALR) 抗体

Calreticulin (CALR)

适用

人, 小鼠, 大鼠, 犬, 豚鼠, 兔, 马, 斑马鱼, Saccharomyces cerevisiae, 山羊

宿主

兔

克隆类型

多克隆

标记

This Calreticulin antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product CALR Primary Antibody

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C-Term

序列

FGNETWGVTK AAEKQMKDKQ DEEQRLKEEE EDKKRKEEEE AEDKEDDEDK

预测反应

Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 92%, Zebrafish: 79%

产品特性

This is a rabbit polyclonal antibody against CALR. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human CALR
anti-Calreticulin (CALR) (AA 196-310) antibody
CALR 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Calreticulin (CALR) (AA 18-193) antibody
CALR 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Calreticulin (CALR) (AA 18-417) antibody
CALR 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7B3D7 unconjugated

anti-Calreticulin (CALR) antibody
CALR 适用: 人, 小鼠 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 1G6A7 unconjugated

anti-Calreticulin (CALR) (N-Term) antibody
CALR 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Calreticulin (CALR) (AA 1-417) antibody
CALR 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G11-1A9 unconjugated

anti-Calreticulin (CALR) antibody
CALR 适用: 人 WB, IHC, IP, ICC, FACS, IF 宿主: 兔 Polyclonal unconjugated

anti-Calreticulin (CALR) (AA 277-305) antibody
CALR 适用: 人, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21112 unconjugated

anti-Calreticulin (CALR) antibody (HRP)
CALR 适用: 人 WB, IHC, IP, ICC, FACS, IF 宿主: 兔 Polyclonal HRP

anti-Calreticulin (CALR) antibody (FITC)
CALR 适用: 人 WB, IHC, IP, ICC, FACS, IF 宿主: 兔 Polyclonal FITC

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 417 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Taguchi, Rho, Yan, Zhang, Zhao, Xu, Tripathi, Wang, Brenner, Kucherlapati, Kucherlapati, Boutin, Wang, DePinho, Feng, Lampe, Hanash: "MAPRE1 as a plasma biomarker for early-stage colorectal cancer and adenomas." in: Cancer prevention research (Philadelphia, Pa.), Vol. 8, Issue 11, pp. 1112-9, (2015) (PubMed).
抗原

Calreticulin (CALR)

别名

CALR

背景

Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.
Alias Symbols: RO, CRT, SSA, cC1qR
Protein Interaction Partner: HUWE1, UBC, LGR4, MDM2, RNF2, SUZ12, rev, AARSD1, THG1L, NSUN2, SH3GLB1, EEF2K, ARPC1A, ANP32B, ACTR2, ARPC1B, ARPC3, ARPC5, TPD52L2, SH3GL1, RPA3, RPA1, PRKACA, PFDN5, LPP, PARK2, UPF2, UBD, SOX2, PDIA3, CLN5, ITGA3, HLA-E, HLA-A, CALR, SLC27A2, env, MTN
Protein Size: 417

分子量

48 kDa

基因ID

811

NCBI登录号

NM_004343, NP_004334

UniProt

P27797

途径

Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response