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DAZAP1 抗体 (C-Term)

DAZAP1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779143
发货至: 中国
  • 抗原 See all DAZAP1 抗体
    DAZAP1 (DAZ Associated Protein 1 (DAZAP1))
    抗原表位
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 24
    • 12
    • 8
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, 犬, 斑马鱼, 豚鼠, 马
    宿主
    • 22
    • 4
    克隆类型
    • 22
    • 4
    多克隆
    标记
    • 22
    • 2
    • 1
    • 1
    This DAZAP1 antibody is un-conjugated
    应用范围
    • 19
    • 11
    • 7
    • 6
    • 4
    • 4
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    LAFPPPPSQA APDMSKPPTA QPDFPYGQYA GYGQDLSGFG QGFSDPSQQP
    预测反应
    Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 93%, Zebrafish: 79%
    产品特性
    This is a rabbit polyclonal antibody against DAZAP1. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human DAZAP1
    Top Product
    Discover our top product DAZAP1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 407 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    DAZAP1 (DAZ Associated Protein 1 (DAZAP1))
    别名
    DAZAP1 (DAZAP1 产品)
    别名
    MGC89358 antibody, DAZAP1 antibody, 2410042M16Rik antibody, mPrrp antibody, DAZ associated protein 1 antibody, DAZ associated protein 1 L homeolog antibody, dazap1 antibody, DAZAP1 antibody, Dazap1 antibody, dazap1.L antibody
    背景
    In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. DAZAP1 is a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL.In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. This gene encodes a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene.In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. This gene encodes a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene.
    Protein Interaction Partner: UBC, WWOX, RPA3, RPA2, RPA1, SUZ12, RNF2, EZH2, BMI1, rev, ITCH, RAD52, VCAM1, ITGA4, FN1, BRCA1, CAND1, COPS5, CUL1, CUL2, CUL3, CUL4B, CUL5, NEDD8, ELAVL1, SUMO2, DAZ1, DAZL,
    Protein Size: 407
    分子量
    45 kDa
    基因ID
    26528
    NCBI登录号
    NM_018959, NP_061832
    UniProt
    Q96EP5
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