CDKN2AIP 抗体 (C-Term)
Quick Overview for CDKN2AIP 抗体 (C-Term) (ABIN2779115)
抗原
See all CDKN2AIP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- AIEALKATLD VFFVPLKELA DLPQNKSSQE SIVCELRCKS VYLGTGCGKS
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against CARF. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human CARF
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 580 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CDKN2AIP (CDKN2A Interacting Protein (CDKN2AIP))
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别名
- CARF
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背景
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CARF was first cloned as a novel binding partner of ARF from a yeast-interactive screen. CARF and ARF colocalize in the perinucleolar region and have a collaborative function. In the nucleoplasm, CARF interacts with p53 and enhances its function. The p53 downregulates CARF in a negative feedback regulatory loop and may also involve p53 antagonist HDM2.
Alias Symbols: CARF
Protein Interaction Partner: UBC, XRN2, RPA3, RPA2, RPA1, WHSC1, VCP, Cdkn2a, MDC1, BRCA1, BARD1, GGH, EPHX1, MDM2, CUL3, SUMO2, RAD21, DHX58, Clp1,
Protein Size: 580 -
分子量
- 64 kDa
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基因ID
- 55602
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NCBI登录号
- NM_017632, NP_060102
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UniProt
- Q9NXV6
抗原
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