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CPSF2 抗体 (N-Term)

Cited in 1 publication. This 兔 多克隆 anti-CPSF2 antibody specifically detects CPSF2 in WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 兔 和 斑马鱼 samples.
产品编号 ABIN2779108
发货至: 中国
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Quick Overview for CPSF2 抗体 (N-Term) (ABIN2779108)

抗原

See all CPSF2 抗体
CPSF2 (Cleavage and Polyadenylation Specific Factor 2, 100kDa (CPSF2))

适用

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人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 兔, 斑马鱼

宿主

  • 21
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克隆类型

  • 24
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多克隆

标记

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This CPSF2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    YAVGKLGLNC AIYATIPVYK MGQMFMYDLY QSRHNTEDFT LFTLDDVDAA

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against CPSF2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human CPSF2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 782 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • 抗原

    CPSF2 (Cleavage and Polyadenylation Specific Factor 2, 100kDa (CPSF2))

    别名

    CPSF2

    背景

    CPSF2 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. It belongs to the metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, CPSF2/YSH1 subfamily.
    Alias Symbols: CPSF100, KIAA1367
    Protein Interaction Partner: RBBP6, UBC, WWOX, EZH2, rev, HECW2, CLK2, NPM1, CPSF3, SYMPK, CSTF2, MDC1, ECT2, BARD1, GTF3C6, FIP1L1, WDR33, POLE3, CPSF1, RALBP1, MED17, GTF3C3, SMARCD3, SMARCA4, POLR2A, CUL3, HNRNPA1, ELAVL1, SUMO2, SMARCAD1, CSTF2T, RRAGA, TBP, PSMA3, CLP1, CDC73, R
    Protein Size: 782

    分子量

    88 kDa

    基因ID

    53981

    NCBI登录号

    NM_017437, NP_059133

    UniProt

    Q9P2I0
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