OAS2 抗体 (Middle Region)
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北京 101111
Quick Overview for OAS2 抗体 (Middle Region) (ABIN2779107)
抗原
See all OAS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- OAS2 Antibody - middle region
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序列
- AKGTALKTGS DADLVVFHNS LKSYTSQKNE RHKIVKEIHE QLKAFWREKE
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预测反应
- Cow: 92%, Dog: 92%, Human: 100%, Pig: 100%, Rabbit: 85%
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产品特性
- This is a rabbit polyclonal antibody against OAS2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human OAS2
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40852-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- OAS2 (2'-5' Oligoadenylate Synthetase 2 (OAS2))
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别名
- OAS2
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背景
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Background Information: OAS2 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication.This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene Name: 2'-5'-oligoadenylate synthetase 2, 69/71 kDa
Alternative Symbols: MGC78578
Protein Name: 2'-5'-oligoadenylate synthase 2
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分子量
- 82kDa
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基因ID
- 4939
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NCBI登录号
- NP_058197
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UniProt
- P29728
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途径
- Hepatitis C
抗原
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