Pre-mRNA Branch Site Protein p14 (SF3B14) (Middle Region) 抗体
Quick Overview for Pre-mRNA Branch Site Protein p14 (SF3B14) (Middle Region) 抗体 (ABIN2779093)
抗原
See all Pre-mRNA Branch Site Protein p14 (SF3B14) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - Middle Region
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序列
 - HLSGFNVCNR YLVVLYYNAN RAFQKMDTKK KEEQLKLLKE KYGINTDPPK
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预测反应
 - Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
 - This is a rabbit polyclonal antibody against SF3B14. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
 - Affinity Purified
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免疫原
 - The immunogen is a synthetic peptide directed towards the middle region of human SF3B14
 
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应用备注
 - Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 125 AA
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - Lot specific
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缓冲液
 - Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
 - Avoid repeated freeze-thaw cycles.
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储存条件
 - -20 °C
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储存方法
 - For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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                                            : "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..."    in: Molecular systems biology, Vol. 3, pp. 89, (2007)         (PubMed).        
 
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                                            : "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..."    in: Molecular systems biology, Vol. 3, pp. 89, (2007)         (PubMed).        
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- Pre-mRNA Branch Site Protein p14 (SF3B14)
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别名
 - SF3B14
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背景
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                        SF3B14 is a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. SF3B14 also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.
Alias Symbols: CGI-110, HSPC175, Ht006, P14, SAP14, SF3B14a
Protein Interaction Partner: UBC, WWOX, SUZ12, EED, PAN2, ITGA4, FN1, SF3B1, VCAM1, SF3B5, THOC6, WDR18, TRA2A, PRPF19, RBMX, SF3B3, PUF60, DHX15, RCC1, APP, U2AF2, ZNF326, ZC3H18, FTSJ3, PHF5A, TRIM55, SF3B2, UTP14A, USP39, PRPF8, BCAS2, SF3B4, THRAP3, EFTUD2, SRSF11, SART1, VTN, U2
Protein Size: 125 - 
                                            
分子量
 - 14 kDa
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基因ID
 - 51639
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NCBI登录号
 - NM_016047, NP_057131
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UniProt
 - Q7RTV0
 
抗原
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