Pre-mRNA Branch Site Protein p14 (SF3B14) (N-Term) 抗体
Quick Overview for Pre-mRNA Branch Site Protein p14 (SF3B14) (N-Term) 抗体 (ABIN2779092)
抗原
See all Pre-mRNA Branch Site Protein p14 (SF3B14) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MAMQAAKRAN IRLPPEVNRI LYIRNLPYKI TAEEMYDIFG KYGPIRQIRV
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against SF3B14. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SF3B14
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 125 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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- Pre-mRNA Branch Site Protein p14 (SF3B14)
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别名
- SF3B14
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背景
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SF3B14 is a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. SF3B14 also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site. This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.
Alias Symbols: CGI-110, HSPC175, Ht006, P14, SAP14, SF3B14a
Protein Interaction Partner: UBC, WWOX, SUZ12, EED, PAN2, ITGA4, FN1, SF3B1, VCAM1, SF3B5, THOC6, WDR18, TRA2A, PRPF19, RBMX, SF3B3, PUF60, DHX15, RCC1, APP, U2AF2, ZNF326, ZC3H18, FTSJ3, PHF5A, TRIM55, SF3B2, UTP14A, USP39, PRPF8, BCAS2, SF3B4, THRAP3, EFTUD2, SRSF11, SART1, VTN, U2
Protein Size: 125 -
分子量
- 14 kDa
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基因ID
- 51639
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NCBI登录号
- NM_016047, NP_057131
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UniProt
- Q9Y3B4
抗原
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