DIS3 抗体 (N-Term)
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北京 101111
Quick Overview for DIS3 抗体 (N-Term) (ABIN2779073)
抗原
See all DIS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- DIS3 Antibody - N-terminal region
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序列
- DIVAVELLPK SQWVAPSSVV LHDEGQNEED VEKEEETERM LKTAVSEKML
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预测反应
- Cow: 79%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 93%, Rabbit: 86%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against DIS3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DIS3
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40793-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))
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别名
- DIS3
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背景
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Background Information: DIS3, belonging to the ribonuclease II (RNB) family, has a 3'-5' exonuclease activity. It is a catalytic component of the exosome 3'->5' exoribonuclease complex required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and for mRNA decay. The protein is implicated in mitotic control and essential for cell division and spore germination. It may be involved in regulating protein dephosphorylation during mitosis.
Gene Name: DIS3 mitotic control homolog (S. cerevisiae)
Alternative Symbols: RRP44, dis3p, EXOSC11, KIAA1008, 2810028N01Rik
Protein Name: Exosome complex exonuclease RRP44
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分子量
- 109kDa
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基因ID
- 22894
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NCBI登录号
- NP_055768
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UniProt
- Q9Y2L1
抗原
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