DIS3 抗体 (N-Term)
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- 抗原 See all DIS3 抗体
- DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 兔, 犬, 马, 豚鼠, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DIS3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- DIVAVELLPK SQWVAPSSVV LHDEGQNEED VEKEEETERM LKTAVSEKML
- 预测反应
- Cow: 79%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 93%, Rabbit: 86%, Rat: 86%
- 产品特性
- This is a rabbit polyclonal antibody against DIS3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DIS3
- Top Product
- Discover our top product DIS3 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 958 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))
- 别名
- DIS3 (DIS3 产品)
- 别名
- EXOSC11 antibody, KIAA1008 antibody, RP11-342J4.3 antibody, RRP44 antibody, bA555G22.1 antibody, dis3p antibody, DIS3 antibody, 2810028N01Rik antibody, RGD1304646 antibody, wu:fb08g12 antibody, dis3 antibody, DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease antibody, DIS3 exosome endoribonuclease and 3'-5' exoribonuclease antibody, DIS3 antibody, Dis3 antibody, dis3 antibody, dis3.L antibody
- 背景
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DIS3, belonging to the ribonuclease II (RNB) family, has a 3'-5' exonuclease activity. It is a catalytic component of the exosome 3'->5' exoribonuclease complex required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and for mRNA decay. The protein is implicated in mitotic control and essential for cell division and spore germination. It may be involved in regulating protein dephosphorylation during mitosis.
Alias Symbols: DKFZp667L1817, FLJ10484, KIAA1008, MGC33035, RP11-342J4.3, RRP44, bA555G22.1, dis3p, EXOSC11
Protein Interaction Partner: SUMO2, UBC, TWF1, NTMT1, EXOSC8, EXOSC10, AICDA, WDR1, STXBP3, PPP5C, SH3PXD2B, EXOSC5, EXOSC4, EXOSC1, EXOSC3, SKIV2L2, EXOSC2, EXOSC7, DIS3, EXOSC9, CUL3, CUL5, SIRT7, BABAM1, EXOSC6, MPP6, ZBTB17,
Protein Size: 958 - 分子量
- 109 kDa
- 基因ID
- 22894
- NCBI登录号
- NM_014953, NP_055768
- UniProt
- Q9Y2L1
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