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DIS3 抗体 (N-Term)

The 兔 多克隆 anti-DIS3 antibody (ABIN2779073) specifically detects DIS3 in WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 兔, 犬, 马, 豚鼠 和 Pig samples.
产品编号 ABIN2779073
发货至: 中国
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Quick Overview for DIS3 抗体 (N-Term) (ABIN2779073)

抗原

See all DIS3 抗体
DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))

适用

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人, 小鼠, 大鼠, Cow, 兔, 犬, 马, 豚鼠, Pig

宿主

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克隆类型

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多克隆

标记

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This DIS3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    DIVAVELLPK SQWVAPSSVV LHDEGQNEED VEKEEETERM LKTAVSEKML

    预测反应

    Cow: 79%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 93%, Rabbit: 86%, Rat: 86%

    产品特性

    This is a rabbit polyclonal antibody against DIS3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human DIS3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 958 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))

    别名

    DIS3

    背景

    DIS3, belonging to the ribonuclease II (RNB) family, has a 3'-5' exonuclease activity. It is a catalytic component of the exosome 3'->5' exoribonuclease complex required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and for mRNA decay. The protein is implicated in mitotic control and essential for cell division and spore germination. It may be involved in regulating protein dephosphorylation during mitosis.
    Alias Symbols: DKFZp667L1817, FLJ10484, KIAA1008, MGC33035, RP11-342J4.3, RRP44, bA555G22.1, dis3p, EXOSC11
    Protein Interaction Partner: SUMO2, UBC, TWF1, NTMT1, EXOSC8, EXOSC10, AICDA, WDR1, STXBP3, PPP5C, SH3PXD2B, EXOSC5, EXOSC4, EXOSC1, EXOSC3, SKIV2L2, EXOSC2, EXOSC7, DIS3, EXOSC9, CUL3, CUL5, SIRT7, BABAM1, EXOSC6, MPP6, ZBTB17,
    Protein Size: 958

    分子量

    109 kDa

    基因ID

    22894

    NCBI登录号

    NM_014953, NP_055768

    UniProt

    Q9Y2L1
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