RBMXL2 抗体 (Middle Region)
Quick Overview for RBMXL2 抗体 (Middle Region) (ABIN2779064)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- SSRDGYSSRD YREPRGFAPS PGEYTHRDYG HSSVRDDCPL RGYSDRDGYG
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预测反应
- Cow: 85%, Dog: 77%, Guinea Pig: 77%, Horse: 77%, Human: 100%, Mouse: 77%, Rabbit: 85%, Rat: 85%
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产品特性
- This is a rabbit polyclonal antibody against RBMXL2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human RBMXL2
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anti-RNA Binding Motif Protein, X-Linked-Like 2 (RBMXL2) (AA 1-90) antibody
RBMXL2 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 6F11 unconjugated
anti-RNA Binding Motif Protein, X-Linked-Like 2 (RBMXL2) (AA 215-264) antibodyRBMXL2 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RNA Binding Motif Protein, X-Linked-Like 2 (RBMXL2) (Middle Region) antibodyRBMXL2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RNA Binding Motif Protein, X-Linked-Like 2 (RBMXL2) antibodyRBMXL2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 392 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RBMXL2 (RNA Binding Motif Protein, X-Linked-Like 2 (RBMXL2))
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别名
- RBMXL2
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背景
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The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. RBMXL2 has two RRM domains that bind RNAs. RBMXL2 has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility.This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind RNAs. This gene is intronless and is thought to be derived from a processed retroposon. However, unlike many retroposon-derived genes, this gene is not a pseudogene. The encoded protein has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2215 AC100875.3 67063-69277 c
Alias Symbols: HNRNPG-T, HNRPGT, HNRNPGT
Protein Interaction Partner: UBC, RABGGTA, FDXACB1, CAND1, COPS5, CUL1, CUL3, CUL4B, SUMO1, DYRK2, TRA2B,
Protein Size: 392 -
分子量
- 43 kDa
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基因ID
- 27288
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NCBI登录号
- NM_014469, NP_055284
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UniProt
- O75526
抗原
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