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PUF60 抗体 (C-Term)

This anti-PUF60 antibody is a 兔 多克隆 antibody detecting PUF60 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠 和 斑马鱼.
产品编号 ABIN2779054
发货至: 中国

Quick Overview for PUF60 抗体 (C-Term) (ABIN2779054)

抗原

See all PUF60 抗体
PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

适用

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人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 斑马鱼

宿主

  • 62
  • 6
  • 1

克隆类型

  • 63
  • 6
多克隆

标记

  • 35
  • 3
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  • 1
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This PUF60 antibody is un-conjugated

应用范围

  • 52
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  • 9
  • 4
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 9
    • 5
    • 4
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    • 2
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    • 2
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    • 1
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    C-Term

    序列

    EIIVKIFVEF SIASETHKAI QALNGRWFAG RKVVAEVYDQ ERFDNSDLSA

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against PUF60. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human PUF60
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 542 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

    别名

    PUF60

    背景

    PUF60 is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription.The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.
    Alias Symbols: FIR, FLJ31379, RoBPI, SIAHBP1
    Protein Interaction Partner: ZG16, ARL8A, LOH12CR1, KIAA1683, MED28, QRICH1, UBE2I, SIAH1, SRSF11, SAP30BP, UPF2, KIAA0907, PUF60, U2AF2, SDCBP, RAD23B, CCNC, SUMO2, SUMO3, CDKN1A, UBC, ERG, EED, H3F3A, FAM129B, VPS29, FAF1, PAPOLA, NUDC, HIRIP3, ZYX, UGP2, TARS, TROVE2, PPM1G, PPP1R
    Protein Size: 542

    分子量

    58 kDa

    基因ID

    22827

    NCBI登录号

    NM_014281, NP_055096
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