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PRPF8 抗体 (N-Term)

This anti-PRPF8 antibody is a 兔 多克隆 antibody detecting PRPF8 in WB. Suitable for 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马 和 兔.
产品编号 ABIN2778986
发货至: 中国
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Quick Overview for PRPF8 抗体 (N-Term) (ABIN2778986)

抗原

See all PRPF8 抗体
PRPF8 (PRP8 Pre-mRNA Processing Factor 8 (PRPF8))

适用

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人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔

宿主

  • 49
  • 3

克隆类型

  • 29
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多克隆

标记

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This PRPF8 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    SHRHSVKSQE PLPDDDEEFE LPEFVEPFLK DTPLYTDNTA NGIALLWAPR

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against PRPF8. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human PRPF8
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 2335 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PRPF8 (PRP8 Pre-mRNA Processing Factor 8 (PRPF8))

    别名

    PRPF8

    背景

    Pre-mRNA splicing occurs in 2 sequential transesterification steps. PRPF8 is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. The gene encoding PRPF8 is a candidate gene for autosomal dominant retinitis pigmentosa.Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: HPRP8, PRP8, PRPC8, RP13
    Protein Interaction Partner: SNRNP200, PRPF8, EFTUD2, UBC, CDKN1A, SUMO2, SUMO3, STAU1, LGR4, NEDD8, ERG, ASB15, WWOX, RPA3, RPA2, RPA1, EED, RNF2, SUZ12, rev, PIN1, NEDD4, FBXO6, PRPF4B, UBD, IGSF8, ICAM1, SND1, SF3B2, SLU7, ZNF830, WDR83, PRPF19, GPKOW, FN1, BCAS2, SF3B4, RBM5, VCA
    Protein Size: 2335

    分子量

    273 kDa

    基因ID

    10594

    NCBI登录号

    NM_006445, NP_006436

    UniProt

    Q6P2Q9
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