PCBP1 抗体 (Middle Region)
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北京 101111
Quick Overview for PCBP1 抗体 (Middle Region) (ABIN2778971)
抗原
See all PCBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- PHATHDLEGP PLDAYSIQGQ HTISPLDLAK LNQVARQQSH FAMMHGGTGF
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against PCBP1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human PCBP1
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anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 100-200) antibody
PCBP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 181-280) antibodyPCBP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 181-280) antibodyPCBP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 208-257) antibodyPCBP1 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) antibodyPCBP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) antibodyPCBP1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 223-234) antibodyVerified PCBP1 适用: 人, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 234-247) antibodyVerified PCBP1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 201-250) antibodyPCBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 356 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "A cytosolic iron chaperone that delivers iron to ferritin." in: Science (New York, N.Y.), Vol. 320, Issue 5880, pp. 1207-10, (2008) (PubMed).
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: "A cytosolic iron chaperone that delivers iron to ferritin." in: Science (New York, N.Y.), Vol. 320, Issue 5880, pp. 1207-10, (2008) (PubMed).
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- PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))
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别名
- PCBP1
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背景
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PCBP1 appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. PCBP1 is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.This intronless gene is thought to be generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 has paralogues PCBP3 and PCBP4 which is thought to arose as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding proteins. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.
Alias Symbols: HNRPE1, HNRPX, hnRNP-E1, hnRNP-X
Protein Interaction Partner: HUWE1, UBC, SNRPA, TP53, SUMO2, SUMO3, TUBGCP3, STAU1, ERG, EED, TUBB6, TUBB2A, PFKP, PFKM, SRPK2, SRPK1, SRPK3, FBXO6, TARDBP, UBD, ADRB2, NPM1, LMNA, HMGA1, CD81, PAN2, PRPF8, PPIG, PRPF3, UBL4A, ANP32A, VCAM1, NOS2, ITGA4, FN1, ATF2, ZNF830, ZCCHC10, P
Protein Size: 356 -
分子量
- 37 kDa
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基因ID
- 5093
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NCBI登录号
- NM_006196, NP_006187
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UniProt
- Q15365
抗原
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