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SF3A1 抗体 (N-Term)

Name: SF3A1 抗体 (N-Term)
SKU: ABIN2778958
Availability: OutOfStock

This anti-SF3A1 antibody is a 兔多克隆 antibody detecting SF3A1 in WB, IHC 和 IF. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠和斑马鱼. This Primary Antibody has been cited in 1 publication.

WB Suggested Anti-SF3A1 Antibody Titration: 0. (SF3A1 抗体 (N-Term))

Rabbit Anti-SF3A1 antibody Paraffin Embedded Tissue: Human Heart cell Cellular Data: cardiac cell Antibody Concentration: 4. (SF3A1 抗体 (N-Term))

IHC

Sample Type : HeLa Primary Antibody Dilution: 4 ug/ml Secondary Antibody : Anti-rabbit Alexa 546 Secondary Antibody Dilution: 2 ug/ml Gene Name : SF3A1 (SF3A1 抗体 (N-Term))

3 images

(1 reference)

产品编号 ABIN2778958

发货至: 中国

Quick Overview for SF3A1 抗体 (N-Term) (ABIN2778958)

抗原

See all SF3A1 抗体

SF3A1 (Splicing Factor 3a, Subunit 1 (SF3A1))

适用

人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 斑马鱼

宿主

兔

克隆类型

多克隆

标记

This SF3A1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Discover our top product SF3A1 Primary Antibody

抗原表位
4

3

2

2

2

1

1

1

1

1

1

1
N-Term

序列

QQTTQQQLPQ KVQAQVIQET IVPKEPPPEF EFIADPPSIS AFDLDVVKLT

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

产品特性

This is a rabbit polyclonal antibody against SF3A1. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human SF3A1
anti-Splicing Factor 3a, Subunit 1 (SF3A1) (AA 249-568) antibody
SF3A1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4D8 unconjugated

anti-Splicing Factor 3a, Subunit 1 (SF3A1) (AA 249-568) antibody
SF3A1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 8H1 unconjugated

anti-Splicing Factor 3a, Subunit 1 (SF3A1) (AA 443-793) antibody
SF3A1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Splicing Factor 3a, Subunit 1 (SF3A1) antibody
SF3A1 适用: 人, 小鼠, 大鼠, 哺乳动物 WB, IP, ICC 宿主: 小鼠 Monoclonal 85D5 unconjugated

anti-Splicing Factor 3a, Subunit 1 (SF3A1) (AA 140-227) antibody
SF3A1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Splicing Factor 3a, Subunit 1 (SF3A1) (AA 121-170) antibody
SF3A1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 斑马鱼, 非洲爪蟾, Pig, Bat, Hamster, 猴, Drosophila melanogaster WB 宿主: 兔 Polyclonal unconjugated

anti-Splicing Factor 3a, Subunit 1 (SF3A1) (AA 72-121) antibody
SF3A1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 非洲爪蟾, 小鸡, Pig, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated

anti-Splicing Factor 3a, Subunit 1 (SF3A1) (AA 249-568) antibody
SF3A1 适用: 人 WB 宿主: 小鼠 Monoclonal 7G6 unconjugated

anti-Splicing Factor 3a, Subunit 1 (SF3A1) (N-Term) antibody
SF3A1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Splicing Factor 3a, Subunit 1 (SF3A1) antibody
SF3A1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 793 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
抗原

SF3A1 (Splicing Factor 3a, Subunit 1 (SF3A1))

别名

SF3A1

背景

SF3A1 is the subunit 1 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 1 belongs to the SURP protein family, named for the SURP motifs that are thought to mediate RNA binding. Subunit 1 has tandemly repeated SURP motifs in its amino-terminal half while its carboxy-terminal half contains a proline-rich region and a ubiquitin-like domain. Binding studies with truncated subunit 1 derivatives demonstrated that the two SURP motifs are necessary for binding to subunit 3 while contacts with subunit 2 may occur through sequences carboxy-terminal to the SURP motifs.This gene encodes subunit 1 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 1 belongs to the SURP protein family, named for the SURP (also called SWAP or Suppressor-of-White-APricot) motifs that are thought to mediate RNA binding. Subunit 1 has tandemly repeated SURP motifs in its amino-terminal half while its carboxy-terminal half contains a proline-rich region and a ubiquitin-like domain. Binding studies with truncated subunit 1 derivatives demonstrated that the two SURP motifs are necessary for binding to subunit 3 while contacts with subunit 2 may occur through sequences carboxy-terminal to the SURP motifs. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: PRP21, PRPF21, SAP114, SF3A120
Protein Interaction Partner: HDAC1, FUS, HUWE1, UBC, RPA3, RPA2, RPA1, WWOX, ZBTB1, SUZ12, EED, RNF2, rev, NR3C1, APBB1, HNRNPR, GAS7, CCDC6, PPP4R2, BRCC3, SMEK1, PRPF40A, GAPVD1, WBP4, TCERG1, HDAC11, HDAC6, SF3A3, DDX42, RBM10, SF3A2, SF1, WHSC1, IL7R, CSNK2A1, WDR77, RBFOX2, SMUR
Protein Size: 793

分子量

89 kDa

基因ID

10291

NCBI登录号

NM_005877, NP_005868

UniProt

Q15459

途径

Ribonucleoprotein Complex Subunit Organization