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SF3B4 抗体 (N-Term)

This 兔 多克隆 anti-SF3B4 antibody specifically detects SF3B4 in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 豚鼠, 兔, Saccharomyces cerevisiae, 马 和 山羊 samples.
产品编号 ABIN2778952
发货至: 中国
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Quick Overview for SF3B4 抗体 (N-Term) (ABIN2778952)

抗原

See all SF3B4 抗体
SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))

适用

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人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 豚鼠, 兔, Saccharomyces cerevisiae, 马, 山羊

宿主

  • 32
  • 5
  • 1

克隆类型

  • 33
  • 5
多克隆

标记

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  • 2
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This SF3B4 antibody is un-conjugated

应用范围

  • 31
  • 20
  • 12
  • 4
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 7
    • 4
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    N-Term

    序列

    QDATVYVGGL DEKVSEPLLW ELFLQAGPVV NTHMPKDRVT GQHQGYGFVE

    预测反应

    Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against SF3B4. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human SF3B4
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 424 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))

    别名

    SF3B4

    背景

    SF3B4 is one of four subunits of the splicing factor 3B. The protein cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
    Alias Symbols: Hsh49, SAP49, SF3b49
    Protein Interaction Partner: NCK2, METTL17, ZCCHC10, UBASH3A, NUB1, HSPB7, PPP1R16B, SS18L1, HNRNPUL1, SF3B2, BAIAP2, SEC24D, FAM115A, RBM39, BAG3, CWF19L2, MAPK9, FUS, FRK, FKBP1A, STAU1, UBC, SUMO1, SUZ12, RNF2, PRPF40A, WBP4, APBB1, SRPK3, DDX42, PRPF8, CHERP, DDX17, BCAS2, EFTUD2
    Protein Size: 424

    分子量

    47 kDa

    基因ID

    10262

    NCBI登录号

    NM_005850, NP_005841

    UniProt

    Q15427
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