HNRNPR 抗体 (N-Term)
(1 reference)Quick Overview for HNRNPR 抗体 (N-Term) (ABIN2778950)
抗原
See all HNRNPR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ANQVNGNAVQ LKEEEEPMDT SSVTHTEHYK TLIEAGLPQK VAERLDEIFQ
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against HNRNPR. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human HNRNPR
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anti-Heterogeneous Nuclear Ribonucleoprotein R (HNRNPR) (AA 95-123), (N-Term) antibody
HNRNPR 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB37032 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein R (HNRNPR) (N-Term) antibodyKO Validated HNRNPR 适用: 人 WB, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein R (HNRNPR) (N-Term) antibodyHNRNPR 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Bat, 小鸡, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein R (HNRNPR) (N-Term) antibodyHNRNPR 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 633 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns." in: Genome biology, Vol. 8, Issue 8, pp. R154, (2008) (PubMed).
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: "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns." in: Genome biology, Vol. 8, Issue 8, pp. R154, (2008) (PubMed).
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- HNRNPR (Heterogeneous Nuclear Ribonucleoprotein R (HNRNPR))
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别名
- HNRNPR
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背景
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HNRNPR belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein has three repeats of quasi-RRM domains that bind to RNAs and also contains a nuclear localization motif. Multiple alternatively spliced transcript variants have been found for this gene. This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs and also contains a nuclear localization motif. Multiple alternatively spliced transcript variants have been found for this gene.
Alias Symbols: FLJ25714, HNRPR, hnRNP-R, hnRNP R
Protein Interaction Partner: PRMT1, KHDRBS2, CEP250, SUMO2, IVNS1ABP, STAU1, UBC, MDM2, WWOX, ZBTB1, RPA3, RPA2, RPA1, RNF2, EED, rev, PPP4R1, MTA2, CCDC6, EHBP1L1, RABEP2, BRCC3, SMEK1, LSM8, LARP7, GAPVD1, CD2AP, WDHD1, SF3A1, TRIM28, HDAC1, NR3C1, POLR2C, POLR2A, MAP4, PARK2, SRPK
Protein Size: 633 -
分子量
- 71 kDa
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基因ID
- 10236
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NCBI登录号
- NM_005826, NP_005817
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UniProt
- O43390
抗原
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