SFPQ 抗体 (Middle Region)
Quick Overview for SFPQ 抗体 (Middle Region) (ABIN2778924)
抗原
See all SFPQ 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- PVIVEPLEQL DDEDGLPEKL AQKNPMYQKE RETPPRFAQH GTFEYEYSQR
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
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产品特性
- This is a rabbit polyclonal antibody against SFPQ. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SFPQ
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anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 269-361) antibody
SFPQ 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 6D7 unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 578-707) antibodySFPQ 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) antibodySFPQ 适用: 人 IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) antibodySFPQ 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (N-Term) antibodySFPQ 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (C-Term) antibodySFPQ 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 191-240) antibodySFPQ 适用: 人, 小鼠, 大鼠, Cow, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 269-362) antibodySFPQ 适用: 人 WB, IHC, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 6D7 unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 444-493) antibodySFPQ 适用: 人, 小鼠, 大鼠, Cow, 小鸡, 马, 豚鼠, 兔, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 499-598) antibodySFPQ 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 707 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SFPQ (Splicing Factor Proline/glutamine-Ric (SFPQ))
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别名
- SFPQ
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背景
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SFPQ is DNA- and RNA binding protein. It is essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as an heteromer with NONO. It binds to pre-mRNA in spliceosome C complex, and specifically binds to intronic polypyrimidine tracts. It interacts with U5 snRNA. It may be involved in a pre-mRNA coupled splicing and polyadenylation process as component of a snRNP-free complex with SNRPA/U1A. SFPQ may be involved in homologous DNA pairing. SFPQ is involved in transcriptional regulation. It binds the DNA sequence 5'-CTGAGTC-3' in the insulin-like growth factor response element (IGFRE) and inhibits IGF-I-stimulated transcriptional activity.
Alias Symbols: POMP100, PSF
Protein Interaction Partner: SNRPA, PTBP1, NONO, HDAC2, FUS, HUWE1, UBC, SUMO2, MDM2, STAU1, RPA3, RPA2, RPA1, ERG, ASB18, ASB12, WWOX, ASB3, EED, rev, TIMM23B, APBB1, PIN1, WBP4, TCERG1, GAS7, PRPF40A, PARK2, UBD, CD81, PAN2, RNF43, WHSC1, VCAM1, SMAD5, ITGA4, FN1, CSNK2A1, BTK, DNA
Protein Size: 707 -
分子量
- 78 kDa
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基因ID
- 6421
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NCBI登录号
- NM_005066, NP_005057
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UniProt
- P23246
抗原
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