PCBP2 抗体 (N-Term)
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- 抗原 See all PCBP2 抗体
- PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 斑马鱼, 豚鼠, 马, 犬, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PCBP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- KKGESVKKMR EESGARINIS EGNCPERIIT LAGPTNAIFK AFAMIIDKLE
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against PCBP2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PCBP2
- Top Product
- Discover our top product PCBP2 Primary Antibody
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anti-Poly(rC) Binding Protein 2 (PCBP2) (AA 1-362) antibody
PCBP2 适用: 人 WB, ELISA, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 5F12 unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (AA 1-130) antibodyPCBP2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) antibodyPCBP2 适用: 人 WB, IF, ICC, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (AA 1-362) antibodyPCBP2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6B6 unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (AA 1-362) antibodyPCBP2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A1 unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (Middle Region) antibodyPCBP2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (AA 171-293) antibodyPCBP2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) antibodyPCBP2 适用: 人, 小鼠, 斑马鱼 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (AA 1-363) antibodyPCBP2 适用: 人 WB, ELISA, IHC, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 5F12 unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (Internal Region) antibodyPCBP2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 366 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))
- 别名
- PCBP2 (PCBP2 产品)
- 别名
- HNRNPE2 antibody, HNRPE2 antibody, hnRNP-E2 antibody, AW412548 antibody, Hnrpx antibody, alphaCP-2 antibody, PCBP3 antibody, fb36h02 antibody, wu:fb36h02 antibody, zgc:55964 antibody, PCBP2 antibody, poly(rC) binding protein 2 antibody, poly(rC) binding protein 2 L homeolog antibody, PCBP2 antibody, Pcbp2 antibody, pcbp2 antibody, pcbp2.L antibody
- 背景
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PCBP2 appears to be multifunctional. It along with PCBP-1 and hnRNPK corresponds to the major cellular poly(rC)-binding proteins. This protein together with PCBP-1 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This gene and PCBP-1 has paralogues PCBP3 and PCBP4 which is thought to arose as a result of duplication events of entire genes.The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: HNRPE2, MGC110998, hnRNP-E2
Protein Interaction Partner: FUS, HUWE1, UBC, SNRPA, SUMO2, SUMO3, CEP250, MDM2, EED, TARDBP, ADRB2, IGSF8, HMGA1, CD81, HMGA2, WDR83, SLU7, CASK, UBL4A, VCAM1, PCBP2, NOS2, ITGA4, FN1, BRCA1, PRPF40A, SF3B2, NKAP, WDR77, PAXIP1, BARD1, PPIB, EEF1A1, FBXO6, UBD, PCBP1, QKI, CDK2, COP
Protein Size: 366 - 分子量
- 39 kDa
- 基因ID
- 5094
- NCBI登录号
- NM_005016, NP_005007
- UniProt
- Q6IPF4
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