AIMP1 抗体 (N-Term)
Quick Overview for AIMP1 抗体 (N-Term) (ABIN2778912)
抗原
See all AIMP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- LLKEKAILQA TLREEKKLRV ENAKLKKEIE ELKQELIQAE IQNGVKQIPF
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against SCYE1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SCYE1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 312 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Endothelial monocyte activating polypeptide-II induced gene expression changes in endothelial cells." in: Cytokine, Vol. 30, Issue 6, pp. 347-58, (2005) (PubMed).
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: "Endothelial monocyte activating polypeptide-II induced gene expression changes in endothelial cells." in: Cytokine, Vol. 30, Issue 6, pp. 347-58, (2005) (PubMed).
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- AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))
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别名
- SCYE1
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背景
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SCYE1 is a cytokine that is specifically induced by apoptosis. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor of SCYE1 (pro-SCYE1) is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex. Therefore, pro-SCYE1 may function in binding RNA as part of the tRNA synthetase complex in normal cells and in stimulating inflammatory responses after proteolytic cleavage in tumor cells.The protein encoded by this gene is a cytokine that is specifically induced by apoptosis. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor of SCYE1 (pro-SCYE1) is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex. Therefore, pro-SCYE1 may function in binding RNA as part of the tRNA synthetase complex in normal cells and in stimulating inflammatory responses after proteolytic cleavage in tumor cells.
Alias Symbols: p43, HLD3, EMAP2, SCYE1, EMAPII
Protein Interaction Partner: AIMP2, TSNAX, UBC, CCAR2, RPL36, EEF1E1, IQGAP1, VARS, RPLP0, RPL27A, RPL23A, RPL21, RPL17, RPL15, RPL13, RPL7A, RARS, QARS, PTBP1, PSMC6, MARS, KARS, IARS, DNAJA1, EIF4G1, EIF2S3, EIF2S1, DARS, PAN2, gag, HSP90B1, MAPK8, LARS, EPRS, APP, COPS5, CUL1, PSM
Protein Size: 312 -
分子量
- 34 kDa
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基因ID
- 9255
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NCBI登录号
- NM_004757, NP_004748
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UniProt
- Q12904
抗原
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