HNRNPC 抗体 (Middle Region)
Quick Overview for HNRNPC 抗体 (Middle Region) (ABIN2778890)
抗原
See all HNRNPC 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- ESEGGADDSA EEGDLLDDDD NEDRGDDQLE LIKDDEKEAE EGEDDRDSAN
-
预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 77%
-
产品特性
- This is a rabbit polyclonal antibody against HNRNPC. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human HNRNPC
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 306 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))
-
别名
- HNRNPC
-
背景
-
This protein is associated with pre-mRNAs in the nucleus and appears to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein acts as a tetramer and is involved in the assembly of 40S hnRNP particles. This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene.
Alias Symbols: C1, C2, HNRNP, HNRPC, MGC104306, MGC105117, MGC117353, MGC131677, SNRPC
Protein Interaction Partner: SUMO1P1, RALYL, RBM41, ZFYVE26, SUMO1, UBE2I, UBC, SDCBP, LMO2, KPNA4, KPNA3, KPNA2, HNRNPC, EPS8, BRIP1, PALB2, BRCA2, BRCA1, BARD1, CEP250, SUMO2, SUMO3, RAD51, IVNS1ABP, STAU1, MDM2, ERG, EED, RNF2, rev, CDKN2A, PARK2, SRPK2, SRPK1, CLK3, TARDBP, YWHAQ
Protein Size: 306 -
分子量
- 34 kDa
-
基因ID
- 3183
-
NCBI登录号
- NM_031314, NP_112604
-
UniProt
- P07910
抗原
-