IREB2 抗体 (Middle Region)
Quick Overview for IREB2 抗体 (Middle Region) (ABIN2778884)
抗原
See all IREB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- IQINLNSIVP SVSGPKRPQD RVAVTDMKSD FQACLNEKVG FKGFQIAAEK
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预测反应
- Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against IREB2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human IREB2
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anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 39-281) antibody
IREB2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 107-216) antibodyIREB2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (Internal Region) antibodyVerified IREB2 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 1-343) antibodyIREB2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 1-250) antibodyIREB2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 1-343) antibodyIREB2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 201-230) antibodyIREB2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB30212 unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 208-238), (Middle Region) antibodyIREB2 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) antibodyIREB2 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 1-343) antibodyIREB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 963 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
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别名
- IREB2
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背景
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IREB2 binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. IREB2 binds to the IRE element in ferritin which results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
Alias Symbols: ACO3, FLJ23381, IRP2, IRP2AD
Protein Interaction Partner: RBCK1, UBC, FAM96A, FAM96B, CIAO1, FBXL5, UBA2, TNPO1, CBS, TERT, USP53, APP, PSMA3, VHL, YBX1,
Protein Size: 963 -
分子量
- 105 kDa
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基因ID
- 3658
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NCBI登录号
- NM_004136, NP_004127
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UniProt
- P48200
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途径
- Transition Metal Ion Homeostasis
抗原
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