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EIF2S1 抗体 (C-Term)

This anti-EIF2S1 antibody is a 兔 多克隆 antibody detecting EIF2S1 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 兔, 豚鼠, 马, 山羊 和 Saccharomyces cerevisiae.
产品编号 ABIN2778883
发货至: 中国

Quick Overview for EIF2S1 抗体 (C-Term) (ABIN2778883)

抗原

See all EIF2S1 抗体
EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))

适用

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人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 兔, 豚鼠, 马, 山羊, Saccharomyces cerevisiae

宿主

  • 57
  • 13
  • 2

克隆类型

  • 53
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多克隆

标记

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This EIF2S1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 8
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    C-Term

    序列

    RGVFNVQMEP KVVTDTDETE LARQMERLER ENAEVDGDDD AEEMEAKAED

    预测反应

    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against EIF2S1. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human EIF2S1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 315 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))

    别名

    EIF2S1

    背景

    The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36 kD), beta (38 kD), and gamma (52 kD). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha.The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36 kD), beta (38 kD, MIM 603908), and gamma (52 kD, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha (Ernst et al., 1987).[supplied by OMIM].
    Alias Symbols: EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A
    Protein Interaction Partner: HUWE1, UBC, SUMO2, SUMO3, RPA3, RPA2, RPA1, RNF2, EIF2S3, DARS, RPS27L, EEF1E1, AIMP1, EIF2S2, RPLP0, RPL27A, RPL15, RPL13, RPL7A, QARS, MARS, MAP4, TERT, NPM1, MMS19, Dlg4, VCAM1, UPF1, ITGA4, FN1, CSNK2A1, EIF2AK2, NCOA5, POP1, STRN, YBX1, DDX1, TMED9,
    Protein Size: 315

    分子量

    35 kDa

    基因ID

    1965

    NCBI登录号

    NM_004094, NP_004085

    UniProt

    P05198

    途径

    Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C
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