PPP1R8 抗体 (Middle Region)
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北京 101111
Quick Overview for PPP1R8 抗体 (Middle Region) (ABIN2778806)
抗原
See all PPP1R8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- PPP1R8 Antibody - middle region
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序列
- PNLAPDVDLT PVVPSAVNMN PAPNPAVYNP EAVNEPKKKK YAKEAWPGKK
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特异性
- This antibody recognizes isoform-gamma
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%
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产品特性
- This is a rabbit polyclonal antibody against PPP1R8. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PPP1R8
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40412-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))
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别名
- PPP1R8
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背景
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Background Information: This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.
Gene Name: Protein phosphatase 1, regulatory subunit 8
Alternative Symbols: ARD1, ARD-1, NIPP1, NIPP-1, PRO2047
Protein Name: Nuclear inhibitor of protein phosphatase 1
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分子量
- 14kDa
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基因ID
- 5511
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NCBI登录号
- NP_002704
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UniProt
- Q12972
抗原
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