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PABP 抗体 (Middle Region)

This 兔 多克隆 antibody specifically detects PABP in WB 和 IHC. It exhibits reactivity toward 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马 和 绵羊.
产品编号 ABIN2778803
发货至: 中国
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Quick Overview for PABP 抗体 (Middle Region) (ABIN2778803)

抗原

See all PABP (PABPC1) 抗体
PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))

适用

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人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马, 绵羊

宿主

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克隆类型

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多克隆

标记

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This PABP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    Middle Region

    序列

    LRPSPRWTAQ GARPHPFQNM PGAIRPAAPR PPFSTMRPAS SQVPRVMSTQ

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

    产品特性

    This is a rabbit polyclonal antibody against PABPC1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human PABPC1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 636 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))

    别名

    PABPC1

    背景

    The poly(A)-binding protein (PABP), which is found complexed to the 3-prime poly(A) tail of eukaryotic mRNA, is required for poly(A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4, MIM 603407), and PABP3 (PABPC3, MIM 604680). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.The poly(A)-binding protein (PABP), which is found complexed to the 3-prime poly(A) tail of eukaryotic mRNA, is required for poly(A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4, MIM 603407), and PABP3 (PABPC3, MIM 604680). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: PAB1, PABP, PABP1, PABPC2, PABPL1
    Protein Interaction Partner: WWP2, PAIP1, TP53, UBC, SUMO2, HAUS1, CEP250, STAU1, MDM2, WWOX, RPA3, RPA2, RPA1, rev, DHX15, UBA1, SGTA, PSMD9, PIN1, P4HB, APEX1, APBB1, TMOD3, WBP4, GNPDA1, ITCH, TARDBP, SRPK2, SRPK1, CLK3, CLK2, PAIP2, CSF2, BRCA1, BAG3, TERT, GSPT2, IGSF8, RBM8A, R
    Protein Size: 636

    分子量

    71 kDa

    基因ID

    26986

    NCBI登录号

    NM_002568, NP_002559

    UniProt

    P11940

    途径

    SARS-CoV-2 Protein Interactome
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