PABP 抗体 (Middle Region)
Quick Overview for PABP 抗体 (Middle Region) (ABIN2778803)
抗原
See all PABP (PABPC1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- LRPSPRWTAQ GARPHPFQNM PGAIRPAAPR PPFSTMRPAS SQVPRVMSTQ
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
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产品特性
- This is a rabbit polyclonal antibody against PABPC1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PABPC1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 636 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))
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别名
- PABPC1
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背景
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The poly(A)-binding protein (PABP), which is found complexed to the 3-prime poly(A) tail of eukaryotic mRNA, is required for poly(A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4, MIM 603407), and PABP3 (PABPC3, MIM 604680). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.The poly(A)-binding protein (PABP), which is found complexed to the 3-prime poly(A) tail of eukaryotic mRNA, is required for poly(A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4, MIM 603407), and PABP3 (PABPC3, MIM 604680). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PAB1, PABP, PABP1, PABPC2, PABPL1
Protein Interaction Partner: WWP2, PAIP1, TP53, UBC, SUMO2, HAUS1, CEP250, STAU1, MDM2, WWOX, RPA3, RPA2, RPA1, rev, DHX15, UBA1, SGTA, PSMD9, PIN1, P4HB, APEX1, APBB1, TMOD3, WBP4, GNPDA1, ITCH, TARDBP, SRPK2, SRPK1, CLK3, CLK2, PAIP2, CSF2, BRCA1, BAG3, TERT, GSPT2, IGSF8, RBM8A, R
Protein Size: 636 -
分子量
- 71 kDa
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基因ID
- 26986
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NCBI登录号
- NM_002568, NP_002559
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UniProt
- P11940
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途径
- SARS-CoV-2 Protein Interactome
抗原
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