ISG20 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for ISG20 抗体 (N-Term) (ABIN2778795)
抗原
See all ISG20 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
原理
- ISG20 Antibody - N-terminal region
-
序列
- GAVLYDKFIR PEGEITDYRT RVSGVTPQHM VGATPFAVAR LEILQLLKGK
-
预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%
-
产品特性
- This is a rabbit polyclonal antibody against ISG20. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Protein A purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ISG20
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8103274
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1.0 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
-
: "HIV-1 Vpr induces interferon-stimulated genes in human monocyte-derived macrophages." in: PLoS ONE, Vol. 9, Issue 8, pp. e106418, (2014) (PubMed).
: "Crystal structure of human ISG20, an interferon-induced antiviral ribonuclease." in: FEBS letters, Vol. 577, Issue 1-2, pp. 111-6, (2004) (PubMed).
-
-
- ISG20 (Interferon Stimulated Exonuclease Gene 20kDa (ISG20))
-
别名
- ISG20
-
背景
-
Background Information: ISG20 belongs to the the exonuclease superfamily. It is exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. It degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. It is involved in the antiviral function of IFN against RNA viruses.
Gene Name: Interferon stimulated exonuclease gene 20 kDa
Alternative Symbols: CD25, HEM45
Protein Name: Interferon-stimulated gene 20 kDa protein
-
分子量
- 20kDa
-
基因ID
- 3669
-
NCBI登录号
- NP_002192
-
UniProt
- Q96AZ6
抗原
-