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ISG20 抗体 (N-Term)

Cited in 2+ publications. This 兔 多克隆 anti-ISG20 antibody specifically detects ISG20 in WB. The antibody is reactive with 人, 大鼠, 小鼠, 犬, 马, Cow, Pig, 豚鼠 和 兔 samples.
产品编号 ABIN2778795
发货至: 中国
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Quick Overview for ISG20 抗体 (N-Term) (ABIN2778795)

抗原

See all ISG20 抗体
ISG20 (Interferon Stimulated Exonuclease Gene 20kDa (ISG20))

适用

人, 大鼠, 小鼠, 犬, 马, Cow, Pig, 豚鼠, 兔

宿主

  • 20
  • 5

克隆类型

  • 22
  • 3
多克隆

标记

  • 20
  • 1
  • 1
  • 1
  • 1
  • 1
This ISG20 antibody is un-conjugated

应用范围

  • 24
  • 11
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    GAVLYDKFIR PEGEITDYRT RVSGVTPQHM VGATPFAVAR LEILQLLKGK

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against ISG20. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human ISG20
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 181 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Zahoor, Xue, Sato, Murakami, Takeshima, Aida: "HIV-1 Vpr induces interferon-stimulated genes in human monocyte-derived macrophages." in: PLoS ONE, Vol. 9, Issue 8, pp. e106418, (2014) (PubMed).

    Horio, Murai, Inoue, Hamasaki, Tanaka, Ohgi: "Crystal structure of human ISG20, an interferon-induced antiviral ribonuclease." in: FEBS letters, Vol. 577, Issue 1-2, pp. 111-6, (2004) (PubMed).

  • 抗原

    ISG20 (Interferon Stimulated Exonuclease Gene 20kDa (ISG20))

    别名

    ISG20

    背景

    ISG20 belongs to the the exonuclease superfamily. It is exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. It degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. It is involved in the antiviral function of IFN against RNA viruses.
    Alias Symbols: CD25, HEM45
    Protein Interaction Partner: UBC,
    Protein Size: 181

    分子量

    20 kDa

    基因ID

    3669

    NCBI登录号

    NM_002201, NP_002192

    UniProt

    Q96AZ6
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