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Aconitase 1 抗体 (N-Term)

This anti-Aconitase 1 antibody is a 兔 多克隆 antibody detecting Aconitase 1 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马 和 Pig.
产品编号 ABIN2778793
发货至: 中国

Quick Overview for Aconitase 1 抗体 (N-Term) (ABIN2778793)

抗原

See all Aconitase 1 (ACO1) 抗体
Aconitase 1 (ACO1)

适用

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  • 1
  • 1
  • 1
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  • 1
  • 1
人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, Pig

宿主

  • 119
  • 4
  • 1

克隆类型

  • 119
  • 5
多克隆

标记

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  • 3
  • 3
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  • 1
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  • 1
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This Aconitase 1 antibody is un-conjugated

应用范围

  • 108
  • 39
  • 34
  • 33
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  • 16
  • 11
  • 11
  • 7
  • 3
  • 2
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 19
    • 17
    • 6
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    • 4
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    • 3
    • 3
    • 3
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    MSNPFAHLAE PLDPVQPGKK FFNLNKLEDS RYGRLPFSIR VLLEAAIRNC

    预测反应

    Cow: 100%, Dog: 93%, Guinea Pig: 91%, Horse: 92%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against ACO1. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human ACO1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 889 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Aconitase 1 (ACO1)

    别名

    ACO1

    背景

    ACO1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). It plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.
    Alias Symbols: IRP1, ACONS, IREB1, IREBP, IREBP1
    Protein Interaction Partner: UBC, FBXL5, DCPS, STRAP, FUBP1, PSMG1, HIST1H2AB, LGALS1, CTPS1, C12orf57, APP, AKT1,
    Protein Size: 889

    分子量

    98 kDa

    基因ID

    48

    NCBI登录号

    NM_002197, NP_002188

    UniProt

    P28271

    途径

    Transition Metal Ion Homeostasis
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