AUH 抗体 (C-Term)
Quick Overview for AUH 抗体 (C-Term) (ABIN2778782)
抗原
See all AUH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- IGMSLAKELI FSARVLDGKE AKAVGLISHV LEQNQEGDAA YRKALDLARE
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 75%
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产品特性
- This is a rabbit polyclonal antibody against AUH. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human AUH
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anti-AU RNA Binding Protein/enoyl-CoA Hydratase (AUH) (AA 68-339) antibody
AUH 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-AU RNA Binding Protein/enoyl-CoA Hydratase (AUH) (AA 38-87) antibodyAUH 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-AU RNA Binding Protein/enoyl-CoA Hydratase (AUH) (AA 44-135) antibodyAUH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G12 unconjugated
anti-AU RNA Binding Protein/enoyl-CoA Hydratase (AUH) (AA 228-277) antibodyAUH 适用: 人, 大鼠, 小鼠, Cow, 兔, 马, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-AU RNA Binding Protein/enoyl-CoA Hydratase (AUH) (C-Term) antibodyAUH 适用: 人, 大鼠, 小鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-AU RNA Binding Protein/enoyl-CoA Hydratase (AUH) (AA 44-135) antibodyAUH 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-AU RNA Binding Protein/enoyl-CoA Hydratase (AUH) (N-Term) antibodyAUH 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-AU RNA Binding Protein/enoyl-CoA Hydratase (AUH) (N-Term) antibodyAUH 适用: 人, 大鼠, 小鼠, 犬, Cow, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-AU RNA Binding Protein/enoyl-CoA Hydratase (AUH) antibodyAUH 适用: 人, 大鼠, 小鼠, 犬 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 339 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- AUH (AU RNA Binding Protein/enoyl-CoA Hydratase (AUH))
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别名
- AUH
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背景
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AU-specific RNA-binding enoyl-CoA hydratase (AUH) protein binds to the AU-rich element (ARE), a common element found in the 3' UTR of rapidly decaying mRNA such as c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. AUH is also homologous to enol-CoA hydratase, an enzyme involved in fatty acid degradation, and has been shown to have intrinsic hydratase enzymatic activity. AUH is thus a bifunctional chimera between RNA binding and metabolic enzyme activity. A possible subcellular localization in the mitochondria has been demonstrated for the mouse homolog of this protein which shares 92 % identity with the human protein. It has been suggested that AUH may have a novel role as a mitochondrial located AU-binding protein. Human AUH is expressed as a single mRNA species of 1.8 kb, and translated as a 40- kDa precursor protein which is subsequently processed to a 32- kDa mature form.AU-specific RNA-binding enoyl-CoA hydratase (AUH) protein binds to the AU-rich element (ARE), a common element found in the 3' UTR of rapidly decaying mRNA such as c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. AUH is also homologous to enol-CoA hydratase, an enzyme involved in fatty acid degradation, and has been shown to have intrinsic hydratase enzymatic activity. AUH is thus a bifunctional chimera between RNA binding and metabolic enzyme activity. A possible subcellular localization in the mitochondria has been demonstrated for the mouse homolog of this protein which shares 92 % identity with the human protein. It has been suggested that AUH may have a novel role as a mitochondrial located AU-binding protein. Human AUH is expressed as a single mRNA species of 1.8 kb, and translated as a 40- kDa precursor protein which is subsequently processed to a 32- kDa mature form.
Protein Interaction Partner: UBC, AUH,
Protein Size: 339 -
分子量
- 37 kDa
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基因ID
- 549
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NCBI登录号
- NM_001698, NP_001689
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UniProt
- Q13825
抗原
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