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AARS 抗体 (C-Term)

The 兔 多克隆 anti-AARS antibody (ABIN2778778) specifically detects AARS in WB 和 IHC. The antibody is reactive with 人, 大鼠, 小鼠, 豚鼠, 马, Cow, 兔, 斑马鱼 和 犬 samples.
产品编号 ABIN2778778
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for AARS 抗体 (C-Term) (ABIN2778778)

抗原

See all AARS 抗体
AARS (Alanyl-tRNA Synthetase (AARS))

适用

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人, 大鼠, 小鼠, 豚鼠, 马, Cow, 兔, 斑马鱼, 犬

宿主

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兔

克隆类型

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多克隆

标记

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This AARS antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    原理

    AARS Antibody - C-terminal region

    序列

    VTGAEAQKAL RKAESLKKCL SVMEAKVKAQ TAPNKDVQRE IADLGEALAT

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

    产品特性

    This is a rabbit polyclonal antibody against AARS. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human AARS
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40369-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    AARS (Alanyl-tRNA Synthetase (AARS))

    别名

    AARS

    背景

    Background Information: The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41 % identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41 % identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.

    Gene Name: Alanyl-tRNA synthetase

    Alternative Symbols: AARS, CMT2N, DEE29, EIEE29

    Protein Name: Alanine--tRNA ligase, cytoplasmic

    分子量

    107kDa

    基因ID

    16

    NCBI登录号

    NP_001596

    UniProt

    P49588
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