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HNRNPL 抗体 (N-Term)

This anti-HNRNPL antibody is a 兔 多克隆 antibody detecting HNRNPL in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼 和 Saccharomyces cerevisiae.
产品编号 ABIN2778776
发货至: 中国

Quick Overview for HNRNPL 抗体 (N-Term) (ABIN2778776)

抗原

See all HNRNPL 抗体
HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))

适用

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人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, Saccharomyces cerevisiae

宿主

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克隆类型

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多克隆

标记

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This HNRNPL antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    RRRSGAMVKM AAAGGGGGGG RYYGGGSEGG RAPKRLKTDN AGDQHGGGGG

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%, Yeast: 85%, Zebrafish: 79%

    产品特性

    This is a rabbit polyclonal antibody against HNRPL. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human HNRPL
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 589 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))

    别名

    HNRPL

    背景

    Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene. Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: P/OKcl.14, hnRNP-L, HNRPL
    Protein Interaction Partner: TP53, FUS, TRIM68, SUMO2, SUMO3, IVNS1ABP, UBC, MDM2, RPA3, RPA2, RPA1, ILF3, HNRNPA2B1, EED, VHL, VEGFA, RNF2, NEDD4, ITCH, FBXO6, HMGA1, vif, TP63, UBL4A, WHSC1, VCAM1, ITGA4, IL7R, IFIT3, IFIT2, FN1, DAB2, CSNK2A1, EIF4A3, MAGOH, HNRNPA3, NPLOC4, LSM14
    Protein Size: 589

    分子量

    65 kDa

    基因ID

    3191

    NCBI登录号

    NM_001533, NP_001524

    UniProt

    P14866
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