EIF4G2 抗体 (C-Term)
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北京 101111
Quick Overview for EIF4G2 抗体 (C-Term) (ABIN2778773)
抗原
See all EIF4G2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- EIF4G2 Antibody - C-terminal region
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序列
- KGFVNILMTS FLQYISSEVN PPSDETDSSS APSKEQLEQE KQLLLSFKPV
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against EIF4G2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human EIF4G2
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40361-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))
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别名
- EIF4G2
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背景
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Background Information: Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. EIF4G2 shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, EIF4G2 functions as a general repressor of translation by forming translationally inactive complexes.
Gene Name: Eukaryotic translation initiation factor 4 gamma, 2
Alternative Symbols: P97, AAG1, DAP5, NAT1
Protein Name: Eukaryotic translation initiation factor 4 gamma 2
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分子量
- 39kDa
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基因ID
- 1982
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UniProt
- P78344
抗原
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