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EIF4G2 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects EIF4G2 in WB 和 IHC. It exhibits reactivity toward 人, 小鼠, 大鼠, Cow, 兔, 犬, 马, 豚鼠 和 Pig.
产品编号 ABIN2778773
发货至: 中国
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Quick Overview for EIF4G2 抗体 (C-Term) (ABIN2778773)

抗原

See all EIF4G2 抗体
EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

适用

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人, 小鼠, 大鼠, Cow, 兔, 犬, 马, 豚鼠, Pig

宿主

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克隆类型

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多克隆

标记

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This EIF4G2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
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    C-Term

    序列

    KGFVNILMTS FLQYISSEVN PPSDETDSSS APSKEQLEQE KQLLLSFKPV

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against EIF4G2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human EIF4G2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 352 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

    别名

    EIF4G2

    背景

    Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. EIF4G2 shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, EIF4G2 functions as a general repressor of translation by forming translationally inactive complexes.
    Alias Symbols: P97, AAG1, DAP5, NAT1
    Protein Interaction Partner: SUMO2, UBC, SKIL, RPA2, ITGA4, FN1, Dlg4, POLDIP3, SLIRP, EIF4G3, RAB7A, EIF4H, EIF4G1, EIF4B, EIF4A1, DCUN1D1, EIF3F, MKNK1, EIF2S2, EIF3A, EIF5, EIF4A2, CASP3, NCBP1, EIF4E, MAGEA6,
    Protein Size: 352

    分子量

    39 kDa

    基因ID

    1982

    NCBI登录号

    NM_001042559

    UniProt

    P78344
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