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DAZL 抗体 (C-Term)

This anti-DAZL antibody is a 兔 多克隆 antibody detecting DAZL in WB. Suitable for 人, 小鼠, 大鼠, 绵羊, Cow, 犬, 山羊, 豚鼠 和 马.
产品编号 ABIN2778769
发货至: 中国

Quick Overview for DAZL 抗体 (C-Term) (ABIN2778769)

抗原

See all DAZL 抗体
DAZL (Deleted in Azoospermia-Like (DAZL))

适用

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人, 小鼠, 大鼠, 绵羊, Cow, 犬, 山羊, 豚鼠, 马

宿主

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克隆类型

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多克隆

标记

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This DAZL antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    EVDPGAEVVP NECSVHEATP PSGNGPQKKS VDRSIQTVVS CLFNPENRLR

    预测反应

    Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 93%, Rat: 86%, Sheep: 93%

    产品特性

    This is a rabbit polyclonal antibody against DAZL. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human DAZL
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 295 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    DAZL (Deleted in Azoospermia-Like (DAZL))

    别名

    DAZL

    背景

    DAZ (Deleted in AZoospermia) is the potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. DAZL is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of the autosomal gene encoding DAZL during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in the Dazl gene have been linked to severe spermatogenic failure and infertility in males.The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: DAZH, DAZL1, DAZLA, MGC26406, SPGYLA
    Protein Interaction Partner: PUM2, DAZ1, UBC, DAZ4, DAZL, DAZAP2, DAZAP1,
    Protein Size: 295

    分子量

    33 kDa

    基因ID

    1618

    NCBI登录号

    NM_001351, NP_001342

    UniProt

    Q92904
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