Splicing factor U2AF 26 kDa subunit (U2AF1L4) (N-Term) 抗体
Quick Overview for Splicing factor U2AF 26 kDa subunit (U2AF1L4) (N-Term) 抗体 (ABIN2778747)
抗原
See all Splicing factor U2AF 26 kDa subunit (U2AF1L4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- KIGVCRHGDR CSRLHNKPTF SQTIVLLNLY RNPQNTAQTA DGSHCHVSDV
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预测反应
- Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against U2AF1L4. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human U2AF1L4
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anti-Splicing factor U2AF 26 kDa subunit (U2AF1L4) (AA 1-202) antibody
U2AF1L4 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Splicing factor U2AF 26 kDa subunit (U2AF1L4) (AA 1-202) antibodyU2AF1L4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Splicing factor U2AF 26 kDa subunit (U2AF1L4) (Internal Region) antibodyVerified U2AF1L4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Splicing factor U2AF 26 kDa subunit (U2AF1L4)
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别名
- U2AF1L4
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背景
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U2AF1L4 is a RNA-binding protein that function as a pre-mRNA splicing factor. It plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. It acts by enhancing the binding of U2AF2 to weak pyrimidine tracts and also participates in the regulation of alternative pre-mRNA splicing. It activates exon 5 skipping of PTPRC during T-cell activation, an event reversed by GFI1. U2AF1L4 binds to RNA at the AG dinucleotide at the 3'-splice site.
Protein Interaction Partner: MDM2, SUZ12, UBC, ELAVL1, GIGYF2,
Protein Size: 220 -
分子量
- 24 kDa
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基因ID
- 199746
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UniProt
- Q8WU68
抗原
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