RAE1 抗体 (C-Term)
Quick Overview for RAE1 抗体 (C-Term) (ABIN2778734)
抗原
See all RAE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- SACCFNHNGN IFAYASSYDW SKGHEFYNPQ KKNYIFLRNA AEELKPRNKK
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against RAE1. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human RAE1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 368 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RAE1 (RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1))
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别名
- RAE1
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背景
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RAE1 is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton.Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: MIG14, MRNP41, Mnrp41, dJ481F12.3, dJ800J21.1
Protein Interaction Partner: TP53, CDC37, DGCR8, YAP1, STK3, EEF2K, SOX2, HNRNPUL1, YWHAQ, UBC, FN1, ZC3HAV1, UBD, DDX39B, NUP98, MAP2, NUMA1, RNA28S5, RNA18S5, LSM14A, IGF2BP3, NXF1, TACC3, DYNLL1, KHSRP, KPNB1, ILF3, COPS6, CUL1, CUL3, Nup214, Nup188, KAT2A, PTTG1, POLR3H, FAM122B,
Protein Size: 368 -
分子量
- 40 kDa
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基因ID
- 8480
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NCBI登录号
- NM_001015885, NP_001015885
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UniProt
- P78406
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途径
- SARS-CoV-2 Protein Interactome
抗原
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