U2AF2 抗体 (N-Term)
(1 reference)Quick Overview for U2AF2 抗体 (N-Term) (ABIN2778722)
抗原
See all U2AF2 (U2AF59) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- EFERQLNENK QERDKENRHR KRSHSRSRSR DRKRRSRSRD RRNRDQRSAS
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against U2AF2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human U2AF2
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anti-U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) (AA 192-471) antibody
U2AF59 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) (AA 141-240) antibodyU2AF59 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5G8 unconjugated
anti-U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) antibodyU2AF59 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) antibodyU2AF59 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) (AA 124-246) antibodyU2AF59 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) (N-Term) antibodyU2AF59 适用: 人, 小鼠, 大鼠, Cow, 马, 犬, 豚鼠, 斑马鱼, 非洲爪蟾, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) (AA 371-420) antibodyU2AF59 适用: 人, 小鼠, 大鼠, Cow, 马, 犬, 豚鼠, 斑马鱼, 猴, Pig, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) (N-Term) antibodyU2AF59 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) (C-Term) antibodyU2AF59 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) antibodyU2AF59 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 471 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Crystallization and preliminary X-ray analysis of a U2AF65 variant in complex with a polypyrimidine-tract analogue by use of protein engineering." in: Acta crystallographica. Section F, Structural biology and crystallization communications, Vol. 62, Issue Pt 5, pp. 457-9, (2006) (PubMed).
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: "Crystallization and preliminary X-ray analysis of a U2AF65 variant in complex with a polypyrimidine-tract analogue by use of protein engineering." in: Acta crystallographica. Section F, Structural biology and crystallization communications, Vol. 62, Issue Pt 5, pp. 457-9, (2006) (PubMed).
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- U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))
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别名
- U2AF2
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背景
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U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2AF2 is the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly.U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date.
Alias Symbols: U2AF65
Protein Interaction Partner: THAP1, PUF60, U2AF1, SNRPA, AES, DACH1, SUMO3, UBC, SUZ12, EED, TERF1, EZH2, RNF2, PRPF40A, TCERG1, APBB1, PIN1, SH3RF2, SRPK2, SRPK1, SF1, SRSF1, RBM39, QKI, SCAF11, PRPF3, RBM10, RBM4, SMAD5, IL7R, HNRNPK, HNRNPD, HLA-DMA, SUGP1, CCAR1, SAP30BP, RBFOX2,
Protein Size: 471 -
分子量
- 52 kDa
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基因ID
- 11338
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NCBI登录号
- NM_001012478, NP_001012496
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UniProt
- Q96HC5
抗原
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