PHAP1 抗体 (N-Term)
Quick Overview for PHAP1 抗体 (N-Term) (ABIN2778668)
抗原
See all PHAP1 (ANP32A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MEMGRRIHLE LRNRTPSDVK ELVLDNSRSN EGKLEGLTDE FEELEFLSTI
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预测反应
- Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 93%, Rat: 86%, Sheep: 77%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against ANP32A. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ANP32A
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 249 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PHAP1 (ANP32A) (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A))
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别名
- ANP32A
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背景
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ANP32A is a novel potent heat-stable inhibitor protein of protein phosphatase 2A. It may play a key role in self-renewing cell populations where it may act in the nucleus to limit their sensitivity to transformation. Being a tumor suppressor, ANP32A represses cell growth through inhibition of transcription by blocking acetylation and phosphorylation of histone H3 and initiating its proapoptotic activity.
Alias Symbols: LANP, MAPM, PP32, HPPCn, PHAP1, PHAPI, I1PP2A, C15orf1
Protein Interaction Partner: UBC, rev, PDLIM5, PLIN3, ARPC1B, OXSR1, EIF4A3, VBP1, TPD52L2, SSB, SRP14, RPA2, PKM, BAG1, SOX2, PCBP1, ESR1, THRB, PPARG, PGR, KPNA6, KPNA5, KPNA1, SUMO2, CHAF1A, HIST1H4A, HIST1H3A, HIST2H2BE, HIST2H2AC, SET, MEPCE, ELAVL1, ADAP1, NSFL1C, HSPB3, AXIN1,
Protein Size: 249 -
分子量
- 29 kDa
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基因ID
- 8125
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NCBI登录号
- NM_006305, NP_006296
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UniProt
- P39687
抗原
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