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PRMT2 抗体 (N-Term)

Name: PRMT2 抗体 (N-Term)
SKU: ABIN183891
Availability: OutOfStock

Cited in 4+ publications. This anti-PRMT2 antibody is a 兔多克隆 antibody detecting PRMT2 in WB 和 IHC. Suitable for 人, 大鼠, 小鼠, Cow, 马, Pig, 豚鼠, 犬和兔.

WB Suggested Anti-PRMT2 Antibody Titration: 0. (PRMT2 抗体 (N-Term))

Image no. 1 for anti-Protein Arginine Methyltransferase 2 (PRMT2) (N-Term) antibody (ABIN183891) (PRMT2 抗体 (N-Term))

Rabbit Anti-PRMT2 Antibody Paraffin Embedded Tissue: Human Liver Cellular Data: Liver cells Antibody Concentration: 4. (PRMT2 抗体 (N-Term))

IHC

PRMT2 antibody - N-terminal region validated by WB using human LCL and mouse brains at 1:1000. (PRMT2 抗体 (N-Term))

Rabbit Anti-PRMT2 Antibody Paraffin Embedded Tissue: Human cardiac cell Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4. (PRMT2 抗体 (N-Term))

IHC

5 images

(4 references)

产品编号 ABIN183891

发货至: 中国

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中国
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Quick Overview for PRMT2 抗体 (N-Term) (ABIN183891)

抗原

See all PRMT2 抗体

PRMT2 (Protein Arginine Methyltransferase 2 (PRMT2))

适用

人, 大鼠, 小鼠, Cow, 马, Pig, 豚鼠, 犬, 兔

宿主

兔

克隆类型

多克隆

标记

This PRMT2 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

抗原表位
8

8

8

4

2

1

1

1

1
N-Term

序列

ESQGEEPAEC SEAGLLQEGV QPEEFVAIAD YAATDETQLS FLRGEKILIL

预测反应

Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against PRMT2. It was validated on Western Blot and immunohistochemistry.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human PRMT2
anti-Protein Arginine Methyltransferase 2 (PRMT2) (N-Term) antibody
PRMT2 适用: 人, 大鼠, 小鼠, Cow, 马, Pig, 豚鼠, 犬, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Protein Arginine Methyltransferase 2 (PRMT2) (AA 22-53) antibody
PRMT2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Protein Arginine Methyltransferase 2 (PRMT2) (AA 1-300) antibody
PRMT2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Protein Arginine Methyltransferase 2 (PRMT2) (AA 1-433) antibody
PRMT2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Protein Arginine Methyltransferase 2 (PRMT2) antibody
PRMT2 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein Arginine Methyltransferase 2 (PRMT2) (N-Term) antibody
PRMT2 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein Arginine Methyltransferase 2 (PRMT2) (N-Term) antibody
PRMT2 适用: 人, 大鼠, 小鼠, Cow, 马, Bat, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Protein Arginine Methyltransferase 2 (PRMT2) (N-Term) antibody
PRMT2 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Protein Arginine Methyltransferase 2 (PRMT2) antibody
PRMT2 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein Arginine Methyltransferase 2 (PRMT2) (AA 22-53), (N-Term) antibody
PRMT2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0027 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 433 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Burton, Muller, Tu, Padilla-Longoria, Guccione, Torres-Padilla: "Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo." in: Cell reports, Vol. 5, Issue 3, pp. 687-701, (2013) (PubMed).

Zhong, Cao, Zu, Hong, Yang, Liu, Xiao, Ding, Zhao, Liu, Wen: "Identification and characterization of novel spliced variants of PRMT2 in breast carcinoma." in: The FEBS journal, Vol. 279, Issue 2, pp. 316-35, (2012) (PubMed).

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Zhong, Cao, Hong, Yang, Zu, Xiao, Liu, Wen: "Identification and expression analysis of a novel transcript of the human PRMT2 gene resulted from alternative polyadenylation in breast cancer." in: Gene, Vol. 487, Issue 1, pp. 1-9, (2011) (PubMed).
抗原

PRMT2 (Protein Arginine Methyltransferase 2 (PRMT2))

别名

PRMT2

背景

The protein arginine methyltransferases (PRMTs) include a family of proteins with related putative methyltransferase domains that modify chromatin and regulate cellular transcription. PRMT2 inhibits NF-kappaB-dependent transcription and promotes apoptosis and it exerts this effect by blocking nuclear export of IkappaB-alpha through a leptomycin-sensitive pathway, increasing nuclear IkappaB-alpha and decreasing NF-kappaB DNA binding. PRMT2 also rendered cells susceptible to apoptosis by cytokines or cytotoxic drugs, likely due to its effects on NF-kappaB.
Alias Symbols: HRMT1L1
Protein Interaction Partner: FIP1L1, SPAG8, RIPK2, BAG6, RB1, HNRNPA1, E2F1, UBC, PSMB3, HHV8GK18_gp81, CPSF7, DMRTB1, HNRNPUL1, PRMT2, THRB, PGR, NCOA6, NCOA1, ESR2, RXRA, PRRC2A, ESR1, PPARG, RARA,
Protein Size: 433

分子量

48 kDa

基因ID

3275

NCBI登录号

NM_001535, NP_001526

UniProt

P55345

途径

Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding