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PRMT2 抗体 (N-Term)

Name: PRMT2 抗体 (N-Term)
SKU: ABIN2778662
Availability: OutOfStock

This anti-PRMT2 antibody is a 兔多克隆 antibody detecting PRMT2 in WB 和 ChIP. Suitable for 人和大鼠. This Primary Antibody has been cited in 2+ publications.

WB Suggested Anti-PRMT2 Antibody Titration: 0. (PRMT2 抗体 (N-Term))

ChIP

2 images

(2 references)

产品编号 ABIN2778662

发货至: 中国

Quick Overview for PRMT2 抗体 (N-Term) (ABIN2778662)

抗原

See all PRMT2 抗体

PRMT2 (Protein Arginine Methyltransferase 2 (PRMT2))

适用

人, 大鼠

宿主

兔

克隆类型

多克隆

标记

This PRMT2 antibody is un-conjugated

应用范围

Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Discover our top product PRMT2 Primary Antibody

抗原表位
8

8

7

4

2

1

1

1

1
N-Term

序列

ERAGCCGYIP ANHVGKHVDE YDPEDTWQDE EYFGSYGTLK LHLEMLADQP

预测反应

Human: 100%, Rat: 79%

产品特性

This is a rabbit polyclonal antibody against PRMT2. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human PRMT2
anti-Protein Arginine Methyltransferase 2 (PRMT2) (N-Term) antibody
PRMT2 适用: 人, 大鼠, 小鼠, Cow, 马, Pig, 豚鼠, 犬, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Protein Arginine Methyltransferase 2 (PRMT2) (AA 22-53) antibody
PRMT2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Protein Arginine Methyltransferase 2 (PRMT2) (AA 1-300) antibody
PRMT2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Protein Arginine Methyltransferase 2 (PRMT2) (AA 1-433) antibody
PRMT2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Protein Arginine Methyltransferase 2 (PRMT2) antibody
PRMT2 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein Arginine Methyltransferase 2 (PRMT2) (N-Term) antibody
PRMT2 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein Arginine Methyltransferase 2 (PRMT2) (N-Term) antibody
PRMT2 适用: 人, 大鼠, 小鼠, Cow, 马, Bat, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Protein Arginine Methyltransferase 2 (PRMT2) (N-Term) antibody
PRMT2 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Protein Arginine Methyltransferase 2 (PRMT2) antibody
PRMT2 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein Arginine Methyltransferase 2 (PRMT2) (AA 22-53), (N-Term) antibody
PRMT2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0027 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 433 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Zhong, Cao, Liu, Liu, Wang, Liu, Chen, Yang, Zhang, Wu, Ding, Hong, Xiao, Zu, Wen: "Nuclear loss of protein arginine N-methyltransferase 2 in breast carcinoma is associated with tumor grade and overexpression of cyclin D1 protein." in: Oncogene, Vol. 33, Issue 48, pp. 5546-58, (2014) (PubMed).

Meyer, Wolf, Obendorf: "PRMT2, a member of the protein arginine methyltransferase family, is a coactivator of the androgen receptor." in: The Journal of steroid biochemistry and molecular biology, Vol. 107, Issue 1-2, pp. 1-14, (2007) (PubMed).
抗原

PRMT2 (Protein Arginine Methyltransferase 2 (PRMT2))

别名

PRMT2

背景

The protein arginine methyltransferases (PRMTs) include a family of proteins with related putative methyltransferase domains that modify chromatin and regulate cellular transcription. PRMT2 inhibits NF-kappaB-dependent transcription and promotes apoptosis and it exerts this effect by blocking nuclear export of IkappaB-alpha through a leptomycin-sensitive pathway, increasing nuclear IkappaB-alpha and decreasing NF-kappaB DNA binding. PRMT2 also rendered cells susceptible to apoptosis by cytokines or cytotoxic drugs, likely due to its effects on NF-kappaB.
Alias Symbols: HRMT1L1, MGC111373
Protein Interaction Partner: FIP1L1, SPAG8, RIPK2, BAG6, RB1, HNRNPA1, E2F1, UBC, PSMB3, HHV8GK18_gp81, CPSF7, DMRTB1, HNRNPUL1, PRMT2, THRB, PGR, NCOA6, NCOA1, ESR2, RXRA, PRRC2A, ESR1, PPARG, RARA,
Protein Size: 433

分子量

49 kDa

基因ID

3275

NCBI登录号

NM_001535, NP_001526

UniProt

P55345

途径

Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding