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PRMT7 抗体 (C-Term)

This anti-PRMT7 antibody is a 兔 多克隆 antibody detecting PRMT7 in WB. Suitable for 人, 小鼠, 大鼠, 犬, 马 和 豚鼠.
产品编号 ABIN2778660
发货至: 中国

Quick Overview for PRMT7 抗体 (C-Term) (ABIN2778660)

抗原

See all PRMT7 抗体
PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

适用

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人, 小鼠, 大鼠, 犬, 马, 豚鼠

宿主

  • 39
  • 4
  • 1

克隆类型

  • 39
  • 5
多克隆

标记

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This PRMT7 antibody is un-conjugated

应用范围

  • 33
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Western Blotting (WB)
  • 抗原表位

    • 7
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    C-Term

    序列

    GEINDQDRTD HYAQALRTVL LPGSVCLCVS DGSLLSMLAH HLGAEQVFTV

    预测反应

    Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Rat: 92%

    产品特性

    This is a rabbit polyclonal antibody against Prmt7. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 692 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

    别名

    Prmt7

    背景

    Prmt7 is a arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. It specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. It plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. It may also play a role in embryonic stem cell (ESC) pluripotency. It also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro, the relevance of such results is however unclear in vivo.
    Alias Symbols: 4933402B05Rik, BC006705, MGC7929
    Protein Interaction Partner: Ctcfl,
    Protein Size: 692

    分子量

    78 kDa

    基因ID

    214572

    NCBI登录号

    NM_145404, NP_663379

    UniProt

    Q922X9

    途径

    Ribonucleoprotein Complex Subunit Organization
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