RNF8 抗体 (C-Term)
Quick Overview for RNF8 抗体 (C-Term) (ABIN2778597)
抗原
See all RNF8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- MEELNRSKKD FEAIIQAKNK ELEQTKEEKE KMQAQKEEVL SHMNDVLENE
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预测反应
- Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against RNF8. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human RNF8
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 485 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RNF8 (Ring Finger Protein 8 (RNF8))
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别名
- RNF8
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背景
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RNF8 contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins.The protein encoded by this gene contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: FLJ12013, KIAA0646
Protein Interaction Partner: TMEM79, HOMEZ, SEPT3, RBFOX2, PNMA2, USP16, WASL, HERC2, MAD1L1, VCP, TNFRSF1A, TNF, BCL10, UBE2N, UBC, NEDD8, JMJD1C, MDC1, EXOSC2, MDM2, BLM, SEPT8, SEPT7, RPSA, H2AFX, RL2, HIST2H2BE, HIST2H2AC, PCNA, RAD50, NBN, MRE11A, UBE2E3, UBE2V1, UBE2E2, UBE2E1,
Protein Size: 485 -
分子量
- 55 kDa
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基因ID
- 9025
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NCBI登录号
- NM_003958, NP_003949
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UniProt
- O76064
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途径
- Production of Molecular Mediator of Immune Response
抗原
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