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- 抗原 See all EYA4 抗体
- EYA4 (Eyes Absent Homolog 4 (EYA4))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 兔, 豚鼠, 犬, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EYA4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MEDTQDLNEQ SVKKTCPEAD VSEPQNSRSM EMQDLASPHA LVGGSDTPGS
- 预测反应
- Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Zebrafish: 85%
- 产品特性
- This is a rabbit polyclonal antibody against Eya4. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Eya4
- Top Product
- Discover our top product EYA4 Primary Antibody
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anti-Eyes Absent Homolog 4 (EYA4) (AA 153-224) antibody
EYA4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Eyes Absent Homolog 4 (EYA4) (AA 1-30), (C-Term) antibodyEYA4 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23878 unconjugated
anti-Eyes Absent Homolog 4 (EYA4) (C-Term) antibodyEYA4 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Eyes Absent Homolog 4 (EYA4) (N-Term) antibodyEYA4 适用: 人, 小鼠, 兔, 豚鼠, 斑马鱼, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 616 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- EYA4 (Eyes Absent Homolog 4 (EYA4))
- 别名
- Eya4 (EYA4 产品)
- 别名
- B130023L16Rik antibody, CMD1J antibody, DFNA10 antibody, EYA transcriptional coactivator and phosphatase 4 antibody, Eya4 antibody, EYA4 antibody
- 背景
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Eya4 is a tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Eya4 promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. It may be involved in development of the eye.
Alias Symbols: B130023L16Rik
Protein Interaction Partner: Six1, Six2, Eya4,
Protein Size: 616 - 分子量
- 67 kDa
- 基因ID
- 14051
- NCBI登录号
- NM_010167, NP_034297
- UniProt
- Q9Z191
- 途径
- Sensory Perception of Sound
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