HIF3A 抗体 (C-Term)
Quick Overview for HIF3A 抗体 (C-Term) (ABIN2778530)
抗原
See all HIF3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- PGSLQDPSTP LLNLNEPLGL GPSLLSPYSD EDTTQPGGPF QPRAGSAQAD
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against HIF3A. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human HIF3A
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 667 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).
: "
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Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).
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- HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))
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别名
- HIF3A
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背景
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HIF3A is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression.The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. At least three transcript variants encoding three different isoforms have been found for this gene.
Alias Symbols: IPAS, MOP7, PASD7, HIF-3A, bHLHe17
Protein Interaction Partner: HSP90AA1, VHL, EGLN3, EGLN1, EGLN2, HIF1A,
Protein Size: 667 -
分子量
- 72 kDa
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基因ID
- 64344
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NCBI登录号
- NM_152794, NP_690007
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UniProt
- Q9Y2N7
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途径
- Warburg Effect
抗原
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