ZNF384 抗体 (C-Term)
Quick Overview for ZNF384 抗体 (C-Term) (ABIN2778449)
抗原
See all ZNF384 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- QQPPPHFQSP GAAPQGGGGG DSNPNPPPQC SFDLTPYKTA EHHKDICLTV
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against ZNF384. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 461 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ZNF384 (Zinc Finger Protein 384 (ZNF384))
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别名
- ZNF384
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背景
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This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7.
Alias Symbols: CAGH1, CAGH1A, CIZ, ERDA2, FLJ59043, NMP4, NP, TNRC1
Protein Interaction Partner: SOX2, UBC, OPTN, tat, HOXC9, CEBPE, TAF15, ZYX, PCBP1, VIM,
Protein Size: 461 -
分子量
- 50 kDa
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基因ID
- 171017
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NCBI登录号
- NM_001039920, NP_001035009
抗原
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