ZNF496 抗体 (N-Term)
Quick Overview for ZNF496 抗体 (N-Term) (ABIN2778404)
抗原
See all ZNF496 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MPTALCPRVL APKESEEPRK MRSPPGENPS PQGELPSPES SRRLFRRFRY
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%
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产品特性
- This is a rabbit polyclonal antibody against ZNF496. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF496
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 587 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ZNF496 (Zinc Finger Protein 496 (ZNF496))
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别名
- ZNF496
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背景
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ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn(II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.
Alias Symbols: NIZP1, ZFP496, ZKSCAN17
Protein Interaction Partner: ZKSCAN4, ZSCAN22, ZNF483, ZNF446, ZSCAN12, ZSCAN21, ARR3, Nsd1, SUMO2, UBC, CBX3, TRIM28, NR3C1, POLR3D, ZZZ3, JADE2, RAI1, SSX3, SUPT5H, PPARG,
Protein Size: 587 -
分子量
- 67 kDa
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基因ID
- 84838
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NCBI登录号
- NM_032752, NP_116141
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UniProt
- Q96IT1
抗原
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