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HDAC4 抗体 (Middle Region)

HDAC4 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2778342
发货至: 中国
  • 抗原 See all HDAC4 抗体
    HDAC4 (Histone Deacetylase 4 (HDAC4))
    抗原表位
    • 15
    • 14
    • 11
    • 9
    • 9
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 115
    • 51
    • 34
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔
    宿主
    • 103
    • 13
    • 1
    克隆类型
    • 103
    • 14
    多克隆
    标记
    • 73
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HDAC4 antibody is un-conjugated
    应用范围
    • 89
    • 51
    • 29
    • 16
    • 14
    • 13
    • 13
    • 10
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    YLDRLPGQKE AHAQAGVQVK QEPIESDEEE AEPPREVEPG QRQPSEQELL
    预测反应
    Cow: 100%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against HDAC4. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human HDAC4
    Top Product
    Discover our top product HDAC4 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1084 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    HDAC4 (Histone Deacetylase 4 (HDAC4))
    别名
    HDAC4 (HDAC4 产品)
    别名
    CG1770 antibody, DHDAC4 antibody, Dmel\\CG1770 antibody, GC1770 antibody, HDAC antibody, HDAC4a antibody, dHDAC4 antibody, dmHDA405 antibody, hdac4 antibody, dana_GLEANR_19966 antibody, DanaGF18710 antibody, GF18710 antibody, HDAC4 antibody, AHO3 antibody, BDMR antibody, HA6116 antibody, HD4 antibody, HDAC-4 antibody, HDAC-A antibody, HDACA antibody, 4932408F19Rik antibody, AI047285 antibody, wu:fa96d08 antibody, wu:fc56f08 antibody, zgc:152701 antibody, histone deacetylase 4 antibody, hypothetical protein antibody, Histone deacetylase 4 antibody, GF18710 gene product from transcript GF18710-RC antibody, PTRG_03699 antibody, PGTG_15512 antibody, HDAC4 antibody, Dana\GF18710 antibody, Hdac4 antibody, hdac4 antibody
    背景
    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC4 belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: HA6116, HD4, HDAC-A, HDACA, KIAA0288, AHO3, BDMR, HDAC-4
    Protein Interaction Partner: UBC, TP53BP1, KRT31, MTUS2, KDM5B, HDAC5, NCOR2, PNMA1, KRT38, YWHAG, KRT40, CCDC136, RINT1, ANKRA2, EFEMP2, LDOC1, GSK3B, GOLGA2, CDR2, BCL6, YWHAQ, YWHAB, YWHAE, SIRT1, UBE2I, TBL1XR1, HDAC4, NCOR1, YWHAZ, YWHAH, SFN, MIF4GD, ZBTB7B, APP, ATF3, JDP2, Bt
    Protein Size: 1084
    分子量
    119 kDa
    基因ID
    9759
    NCBI登录号
    NM_006037, NP_006028
    UniProt
    P56524
    途径
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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