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HDAC4 抗体 (N-Term)

Name: HDAC4 抗体 (N-Term)
SKU: ABIN2778341
Availability: OutOfStock

This 兔多克隆 anti-HDAC4 antibody specifically detects HDAC4 in WB. The antibody is reactive with 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 豚鼠和马 samples.

WB Suggested Anti-HDAC4 Antibody Titration: 0. (HDAC4 抗体 (N-Term))

Rabbit Anti-HDAC4 Antibody Formalin Fixed Paraffin Embedded Tissue: Human Testis Tissue Observed Staining: Cytoplasm Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0. (HDAC4 抗体 (N-Term))

IHC

2 images

产品编号 ABIN2778341

发货至: 中国

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Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HDAC4 抗体 (N-Term) (ABIN2778341)

抗原

See all HDAC4 抗体

HDAC4 (Histone Deacetylase 4 (HDAC4))

适用

人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 豚鼠, 马

宿主

兔

克隆类型

多克隆

标记

This HDAC4 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product HDAC4 Primary Antibody

抗原表位
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N-Term

序列

EKQHREQKLQ QLKNKEKGKE SAVASTEVKM KLQEFVLNKK KALAHRNLNH

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 85%

产品特性

This is a rabbit polyclonal antibody against HDAC4. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human HDAC4
anti-Histone Deacetylase 4 (HDAC4) (AA 904-1076) antibody
HDAC4 适用: 小鼠 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 4 (HDAC4) (AA 551-648) antibody
HDAC4 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2B11 unconjugated

anti-Histone Deacetylase 4 (HDAC4) (AA 456-592) antibody
HDAC4 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 7E2E6 unconjugated

anti-Histone Deacetylase 4 (HDAC4) (AA 456-592) antibody
HDAC4 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5E4A5 unconjugated

anti-Histone Deacetylase 4 (HDAC4) (AA 451-650) antibody
HDAC4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 4 (HDAC4) (AA 1049-1077) antibody
HDAC4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 4 (HDAC4) (AA 530-630) antibody
HDAC4 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 4 (HDAC4) antibody
HDAC4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 4 (HDAC4) (pSer220), (pSer246), (pSer259) antibody
HDAC4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 4 (HDAC4) antibody
HDAC4 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 1084 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

HDAC4 (Histone Deacetylase 4 (HDAC4))

别名

HDAC4

背景

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC4 belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HA6116, HD4, HDAC-A, HDACA, KIAA0288, AHO3, BDMR, HDAC-4
Protein Interaction Partner: UBC, TP53BP1, KRT31, MTUS2, KDM5B, HDAC5, NCOR2, PNMA1, KRT38, YWHAG, KRT40, CCDC136, RINT1, ANKRA2, EFEMP2, LDOC1, GSK3B, GOLGA2, CDR2, BCL6, YWHAQ, YWHAB, YWHAE, SIRT1, UBE2I, TBL1XR1, HDAC4, NCOR1, YWHAZ, YWHAH, SFN, MIF4GD, ZBTB7B, APP, ATF3, JDP2, Bt
Protein Size: 1084

分子量

119 kDa

基因ID

9759

NCBI登录号

NM_006037, NP_006028

UniProt

P56524

途径

Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process