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MEF2A 抗体 (N-Term)

This anti-MEF2A antibody is a 兔 多克隆 antibody detecting MEF2A in WB. Suitable for 人, 小鼠, 大鼠, Cow, 马, 犬, Pig, 兔 和 斑马鱼.
产品编号 ABIN2778339
发货至: 中国

Quick Overview for MEF2A 抗体 (N-Term) (ABIN2778339)

抗原

See all MEF2A 抗体
MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

适用

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人, 小鼠, 大鼠, Cow, 马, 犬, Pig, 兔, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This MEF2A antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    YNEPHESRTN SDIVEALNKK EHRGCDSPDP DTSYVLTPHT EEKYKKINEE

    预测反应

    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against MEF2A. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human MEF2A
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 507 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

    别名

    MEF2A

    背景

    The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD, myogenin, MYF5, and MRF4 are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes.The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ADCAD1, RSRFC4, RSRFC9, mef2
    Protein Interaction Partner: HDAC7, HDAC5, HDAC3, TAF8, GNG12, TBP, GNB2, ERBB2IP, NDUFB9, DDB1, Dlg4, PHB2, ASCL1, SUMO1, UBE2I, SUMO2, HNRNPA1, UBC, MEF2D, HDAC1, EP300, HDAC4, ACTN4, THRA, HDAC9, MAPK7, CASP7, SMAD2, SMAD4, MEF2A, CASP3, MAPK14, TEAD1, MYOG, MYOD1, CDK5, VGLL4,
    Protein Size: 507

    分子量

    55 kDa

    基因ID

    4205

    NCBI登录号

    NM_005587, NP_005578

    UniProt

    Q02078

    途径

    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
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