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MED6 抗体 (Middle Region)

This anti-MED6 antibody is a 兔 多克隆 antibody detecting MED6 in WB 和 ChIP. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 马, 兔 和 豚鼠.
产品编号 ABIN2778335
发货至: 中国
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Quick Overview for MED6 抗体 (Middle Region) (ABIN2778335)

抗原

See all MED6 抗体
MED6 (Mediator Complex Subunit 6 (MED6))

适用

  • 45
  • 9
  • 7
  • 6
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠

宿主

  • 40
  • 5

克隆类型

  • 42
  • 3
多克隆

标记

  • 28
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MED6 antibody is un-conjugated

应用范围

  • 37
  • 21
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
  • 抗原表位

    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    ALLLDLRQKF PPKFVQLKPG EKPVPVDQTK KEAEPIPETV KPEEKETTKN

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against MED6. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human MED6
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 246 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    MED6 (Mediator Complex Subunit 6 (MED6))

    别名

    MED6

    背景

    MED6 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. And mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    Alias Symbols: NY-REN-28
    Protein Interaction Partner: TARDBP, UBC, CDK19, CDK8, MED10, MED23, CCNC, MED19, MED26, FBXW7, MED11, MED28, MED29, MED4, MED12, MED7, MED21, MED1, SMARCA4, BCL6, SUZ12, CUL1, SKP1, CTDP1, MED25, SREBF1, MED15, VDR, OBFC1, MED18, ZC3H13, TADA2A, RARA, PARP1, SMAD3, SMAD2, SMAD1, MED
    Protein Size: 246

    分子量

    28 kDa

    基因ID

    10001

    NCBI登录号

    NM_005466, NP_005457

    UniProt

    O75586

    途径

    Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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