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MED17 抗体 (N-Term)

This anti-MED17 antibody is a 兔 多克隆 antibody detecting MED17 in WB, IHC 和 ChIP. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马 和 兔.
产品编号 ABIN2778320
发货至: 中国

Quick Overview for MED17 抗体 (N-Term) (ABIN2778320)

抗原

See all MED17 抗体
MED17 (Mediator Complex Subunit 17 (MED17))

适用

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人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔

宿主

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克隆类型

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多克隆

标记

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This MED17 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)
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    N-Term

    序列

    AAQILLKGAE RLTKSVTENQ ENKLQRDFNS ELLRLRQHWK LRKVGDKILG

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against CRSP6. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human CRSP6
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 651 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    MED17 (Mediator Complex Subunit 17 (MED17))

    别名

    CRSP6

    背景

    The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
    Alias Symbols: CRSP6, CRSP77, DRIP80, TRAP80
    Protein Interaction Partner: UBC, BRCA1, CDK19, CDK8, MED26, POLR2C, ESR2, MED19, FBXW7, EPAS1, TFIP11, MED24, MED21, MED14, MED11, MED28, WDR33, CPSF2, UBD, BCL6, SMARCA4, SUZ12, MED10, CTDP1, SREBF1, MED25, MED15, TRA, MED1, OBFC1, MED18, ZC3H13, MED12, QKI, TRIP4, TADA2A, SUPT7L,
    Protein Size: 651

    分子量

    73 kDa

    基因ID

    9440

    NCBI登录号

    NM_004268, NP_004259

    UniProt

    Q9NVC6

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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